4MPF CAS 5337-93-9 4-methylpropiophenone Product Information
| Product Name: | 4-Methylpropiophenone |
| Synonyms: | 4′-Methylpropiophenone; 1-(4-Methylphenyl)-1-propanone; 1-(4-Tolyl)-1-propanone; 4′-Methylpropiophenone; Ethyl 4-Methylphenyl Ketone; Ethyl p-Tolyl Ketone; NSC 852; p-Methylpropiophenone |
| CAS NO: | 5337-93-9 |
| EINECS: | 226-267-5 |
| Molecular Formula: | C₁₀H₁₂O |
| Molecular Weight: | 148.2 |
| Melting Point: | 7.2 °C |
| Boiling Point: | 238-239 °C(lit.) |
| Density: | 0.993 g/mL at 25 °C(lit.) |
| Appearance: | Colourless |
| Storage: | Inert atmosphere,Room Temperature |
| Solubility: | Soluble in chloroform and hexane. |
What is CAS 5337-93-9 4-methylpropiophenone?
4′-methylpropiophenone has been reported to be used in the synthesis of pharmaceutical compounds such as tolperisone and other muscle relaxants. The substance is also a starting material in the synthesis of 4-methylmethcathinone (mephedrone). Mephedrone has been encountered as a ‘legal high’ and on the illicit drug market masquerading as cocaine (in powder form), MDMA (in tablet form) and as an adulterant. According to the 2016 European Drugs Market Report produced by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), mephedrone has created a specific demand and carved its own distinct market share.
Application
4′-Methylpropiophenone can be used as a building block to synthesize:
N-(4-Chlorophenyl)-N′-[1-(4-methylphenyl)propyl]urea as a potential CRAC channel inhibitor.
Mono and trinuclear cobaloxime/organocobaloxime complexes, which are used as efficient catalysts for the synthesis of cyclic carbonates.
Tolperisone (TOL) via acid-catalyzed reaction with piperidine hydrochloride and 1,2-dioxolane.
4MPF CAS 5337-93-9 4-methylpropiophenone Product Picture
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